Our project plans to assess the neural mechanisms of high blood pressure in obesity-associated hypertension. The inclusion of SphygmoCor technology would advance our research by adding the assessment of the hemodynamic (pressure-flow relations) determinants of high blood pressure. Coupling the assessments of central arterial stiffness and its consequences for central and peripheral blood pressure will provide high-resolution assessments of the causes of high blood pressure in obesity, hypertension and obesity-associated hypertension. Previous studies have typically focused on either sympathetic neural control or arterial structure/function. The provision of SphygmoCor equipment will facilitate an investigation into whether elevated NPY during stress mediates the link between elevated sympathetic nervous system activity, elevated arterial stiffness and abnormal central hemodynamics. Specifically, participants will perform at home blood pressure monitoring using the CONNEQT Pulse and will upload their vascular biometric data to the server so investigators can access a 14-day report. The home blood pressure assessments will engage individuals with their blood pressure and via consultation with our clinical staff further their understanding of its importance for their heart and other major organs. The SphgmoCor Xcel will be used to conduct pulse wave analysis and velocity (PWA/V) measurements in the laboratory. The combined assessments of at home central and peripheral blood pressure and measurements of (PWA/V) will provide comprehensive of assessment of each participants blood pressure. These data will add significantly to our research program but most importantly provide unique and novel information to each participant and their primary care physician to aid in their care.