The EPICure Study: Association Between Hemodynamics and Lung Function at 11 Years After Extremely Preterm Birth
May 11, 2012Low Testosterone in Men Predicts Impaired Arterial Elasticity and Microvascular Function
May 12, 2015Body Compositional and Cardiometabolic Effects of Testosterone Therapy in Obese Men with Severe Obstructive Sleep Apnea: A Randomized Placebo-Controlled Trial
Untreated obstructive sleep apnea (OSA), especially when combined with obesity and male gender, increases all-cause and cardiovascular mortality. Androgen deficiency is common in both obese men and those with OSA. Led by Hoyos, a study investigated the impact of testosterone therapy on vascular biomarkers, specifically augmentation index (AIx), in 67 obese men with OSA. Although testosterone therapy did not affect weight, it significantly improved AIx and body composition. Monitoring vascular biomarkers in individuals with obesity or OSA could guide treatment decisions and assess the beneficial effects of testosterone therapy.