Wellness and Longevity

Personalized Health & Wellness Strategies with Vascular Health Insights

Maximize Healthspan with Vascular Biomarkers

Vascular biomarkers that measure arterial stiffness and vascular function are key to promoting longevity and improving healthspan. They enable early detection of cardiovascular dysfunction, allowing for timely, personalized interventions to slow or reverse disease progression.

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Vascular Biomarkers Explained

Vascular biomarkers are revolutionizing not only cardiovascular health management but also clinical research and personal wellness strategies.

These critical indicators offer a comprehensive evaluation of the cardiovascular system's health across a broad spectrum, from clinical trials to individual health monitoring. By assessing key markers such as endothelial function, arterial stiffness, and coronary flow reserve, they enable a nuanced understanding of cardiovascular risks and conditions.

This valuable insight facilitates early intervention, personalized health optimization, and the development of targeted treatments in clinical settings, significantly advancing patient care and wellness initiatives.

Brachial Blood Pressure

What it Is
Brachial blood pressure measures the pressure of blood at the brachial artery using a blood pressure cuff.

Why it Matters
High blood pressure is a major risk factor for heart disease and stroke, both of which are leading causes of death in the US.

Central Blood Pressure

What it Is
Calculated using pulse wave analysis and a traditional brachial cuff, central blood pressure measures pressure at the root of the aorta.

Why it Matters
Central blood pressure reflects key vascular issues such as arterial stiffness, which makes it a more accurate predictor of subclinical cardiovascular disease than traditional brachial blood pressure alone.

Subendocardial Viability Ratio

What it Is
Subendocardial viability ratio measures the supply of blood that flows to your inner heart muscle in relation to demand.

Why it Matters
SEVR offers insight into how well a person’s heart can handle the stress of exercise.

Augmentation Pressure

What it Is
Augmentation pressure refers to the increase in central aortic pressure caused pressure wave reflection.

Why it Matters
A marker of arterial stiffness, elevated augmentation pressure is associated with cardiovascular risk factors as well as increased cardiovascular morbidity and mortality.

Augmentation Index

What it Is
An indirect measure of arterial stiffness that increases with age, augmentation index reflects the burden stiff arteries place on the heart.

Why it Matters
Chronic stress on the heart and the cardiovascular system can lead to heart failure and hypertrophy (enlarged heart).

Central Pulse Pressure

What it Is
The height of pressure at the heart, central pulse pressure shows the pressure to which key organs like the heart, brain, and kidneys are exposed.

Why it Matters
Central pulse pressure helps identify the risk of end organ damage to key organs like the brain, kidney and heart.

Medical Grade Heart Rate
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Pulse Wave Velocity

What it Is
Pulse wave velocity measures arterial stiffness.

Why it Matters
Increases in arterial stiffness are generally based on the loss of elasticity in the aorta artery walls over time and increases the strain on the heart from heightened pressures. Increased aortic stiffness using PWV is a validated predictor of cardiovascular events and all-cause mortality.

 
cbpCentral Blood Pressure

What it Is
Calculated using pulse wave analysis and a traditional brachial cuff, central blood pressure measures pressure at the root of the aorta.

Why it Matters
Central blood pressure reflects key vascular issues such as arterial stiffness, which makes it a more accurate predictor of subclinical cardiovascular disease than traditional brachial blood pressure alone.

 
bbpBrachial Blood Pressure

What it Is
Brachial blood pressure measures the pressure of blood at the brachial artery using a blood pressure cuff.

Why it Matters
High blood pressure is a major risk factor for heart disease and stroke, both of which are leading causes of death in the US.

 
sevrSubendocardial Viability Ratio

What it Is
Subendocardial viability ratio measures the supply of blood that flows to your inner heart muscle in relation to demand.

Why it Matters SEVR offers insight into how well a person’s heart can handle the stress of exercise.

 
medical grade heart rateMedical Grade Heart Measurement

What it Is
A beat-to-beat heart rate measurement on par with standard ECG-based methods.

Why it Matters
A consistently high resting heart rate may be a sign of coronary heart disease and is associated with a greater risk of stroke.

 
cppCentral Pulse Pressure

What it Is
The height of pressure at the heart, central pulse pressure shows the pressure to which key organs like the heart, brain, and kidneys are exposed.

Why it Matters
Central pulse pressure helps identify the risk of end organ damage to key organs like the brain, kidney and heart.

 
cppPulse Wave Velocity

What it Is
Pulse wave velocity measures arterial stiffness.

Why it Matters
Increases in arterial stiffness are generally based on the loss of elasticity in the aorta artery walls over time and increases the strain on the heart from heightened pressures. Increased aortic stiffness using PWV is a validated predictor of cardiovascular events and all-cause mortality.

 
augmentation pressureAugmentation Pressure

What it Is
Augmentation pressure refers to the increase in central aortic pressure caused pressure wave reflection.

Why it Matters
A marker of arterial stiffness, elevated augmentation pressure is associated with cardiovascular risk factors as well as increased cardiovascular morbidity and mortality.

 
augmentation indexAugmentation Index

What it Is
An indirect measure of arterial stiffness that increases with age, augmentation index reflects the burden stiff arteries place on the heart.

Why it Matters
Chronic stress on the heart and the cardiovascular system can lead to heart failure and hypertrophy (enlarged heart).

Hover over each biomarker above to learn more
Spotlight

Dr. Joseph Raffaele

Longevity Medicine Specialist

Utilizing digital biomarkers to improve cardiovascular health of patients

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Charting a Path to Comprehensive Personalized Wellness

Incorporating vascular biomarkers effectively into broader health management represents a significant shift towards more proactive and personalized healthcare strategies. This paradigm shift is critical in enhancing patient care across multiple aspects of health, ultimately leading to improved overall health outcomes and a higher quality of life for individuals.

Comprehensive Checkup

SphygmoCor XCEL is a sophisticated clinical tool designed to precisely measure essential vascular biomarkers like arterial stiffness and central blood pressure. Its integration into routine clinical practice enables a proactive approach to cardiovascular care, significantly enhancing patient outcomes.

Explore XCEL

Self Monitoring

CONNEQT Pulse is an innovative home monitoring tool that effectively tracks vascular health from the comfort of one's home. Its user-friendly design makes it ideal for daily health monitoring, promoting proactive health management and enhancing patient engagement with their cardiovascular health.

Explore Pulse

Extended Monitoring

Oscar 2 excels as a leading ambulatory monitor, designed for extended wear in non-clinical settings to capture vascular biomarkers continuously. It monitors blood pressure and arterial health over 24 hours, revealing a patient’s vascular dynamics under normal conditions.

Explore Oscar 2

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