Left ventricular hypertrophy (LVH) is a common cardiovascular complication of chronic kidney disease (CKD), closely associated with increased cardiovascular morbidity and mortality. Ruyi Cai and colleagues demonstrated that even within a CKD population, Central pulse pressure exhibited higher sensitivity and specificity compared to brachial pulse pressure for determining LVH. The study’s findings indicate that CBP serves as a superior predictor of LVH risk. Advocating for early identification and treatment of elevated CBP mitigates the risk of LVH and subsequent cardiovascular complications in CKD patients.