Comparison of Risk of Target Organ Damage in Different Phenotypes of Arterial Stiffness and Central Aortic Blood Pressure

Zuo’s team investigated the correlation of various vascular phenotypes, such as arterial stiffness and blood pressure status, and target organ damage. The results found that patients exhibiting both elevated pulse wave velocity (PWV) and central blood pressure (CBP) face heightened risks of chronic kidney disease (CKD). Notably, individuals with solely elevated CBP display an increased risk of abnormal albumin-to-creatinine ratio (ACR), signifying early stages of renal impairment. This suggests that elevation of central aortic blood pressure, distinct from PWV, may serve as an early indicator of renal impairment.