61-Year-Old Male with Hypertension and Comorbidities
February 14, 2024
41-Year-Old Male with Untreated Hypertension
February 14, 2024

Personalized Treatment Regimen Following Pulse Wave Analysis

33-Year-Old Male with Persistent Systolic Hypertension*

Patient Medical History

  • Prescribed an ACE inhibitor for systolic and diastolic blood pressure management
  • Diagnosed with hypertension 1 year ago
  • No comorbidities
  • Nonsmoker
  • Results from electrocardiography were normal
    1 year ago

Digital Vascular Biomarker Assessment

Brachial Blood Pressure† 144/74 mmHg
Central Systolic Pressure 114 mmHg
Central Pulse Pressure Amplification 79%


This male patient’s central systolic blood pressure of 114 mmHg is 10 mmHg less than the proposed upper limit of 124 mmHg. He has a pulse pressure amplification of 79%. The central pressure profile was interpreted as supporting current management, and his medication was not increased.

This instance shows a case of persistent brachial systolic hypertension on therapy with acceptable central pressure readings. The central pressure readings provide support for not altering current management. As acknowledged by the authors, the intent here is not to overrule brachial blood pressure management, but to allow the use of clinical judgment in decision-making in select clinical scenarios, as recommended in the JNC 8 document.1

*Townsend RR et al. Journal of Clinical Hypertension. 2015; 17:7, 503–513. DOI: 10.1111/jch.12574:   http://bit.ly/2gc5mdD

Reference 1:  JNC 8 Guidelines for the Management of Hypertension in Adults | AAFP

Figure 5. Peripheral and Central Pressure Waveforms

BBP indicates brachial blood pressure systolic/diastolic; CBP, central blood pressure systolic/diastolic; CPP, central pulse pressure; AIx, augmentation index; HR, heart rate; bpm, beats per minute.

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